同义名 :	-
	CAS号 :	72-14-0
	货号 :	A227334
	分子式 :	C9H9N3O2S2
	纯度 :	98+%
	分子量 :	255.32
	MDL号 :	MFCD00005319
	存储条件：	Pure form Sealed in dry,2-8°C In solvent -20°C:3-6个月-80°C:12个月
	溶解度 :	-
	动物实验配方：

生物活性

描述

Sulfathiazole, an organosulfur compound, is used as a short-acting sulfonamide antibiotic.Recovery from spiked manure slurry samples is 64% for Sulfathiazole at pH 9. Sulfathiazole has acidity constant of pKa of 7.1and retention times (tR) of 7.8. S/N values for Sulfathiazole are above 100 at the 1 mg/kg level[3]. Sulfathiazole sorption to inorganic sorbents exhibited pronounced pH dependence consistent with sorbate speciation and sorbent charge properties.Sulfathiazole cations were most important for sorption to clay minerals [4]. The sorption of STZ (Sulfathiazole) on GMC-treated(giant Miscanthus) soils is greatly enhanced, mainly through the greater micropore surfaces, the abundance of hydrophilic functional groups over time, and π+-π electron donor-acceptor interaction at low pH[5].

实验方案
	1mg	5mg	10mg
1 mM 5 mM 10 mM	3.92mL 0.78mL 0.39mL	19.58mL 3.92mL 1.96mL	39.17mL 7.83mL 3.92mL

参考文献

[1]Perez S, Eichhorn P, Aga DS. Evaluating the biodegradability of sulfamethazine, sulfamethoxazole, sulfathiazole, and trimethoprim at different stages of sewage treatment. Environ Toxicol Chem. 2005 Jun;24(6):1361-7. [2]Haller MY, Muller SR, et al. Quantification of veterinary antibiotics (sulfonamides and trimethoprim) in animal manure by liquid chromatography-mass spectrometry. J Chromatogr A. 2002 Apr 5;952(1-2):111-20. [3]Haller MY, Müller SR, McArdell CS, Alder AC, Suter MJ. Quantification of veterinary antibiotics (sulfonamides and trimethoprim) in animal manure by liquid chromatography-mass spectrometry. J Chromatogr A. 2002;952(1-2):111–120 [4]Kahle M, Stamm C. Time and pH-dependent sorption of the veterinary antimicrobial sulfathiazole to clay minerals and ferrihydrite. Chemosphere. 2007;68(7):1224–1231 [5]Kim H, Kim J, Kim M, Hyun S, Moon DH. Sorption of sulfathiazole in the soil treated with giant Miscanthus-derived biochar: effect of biochar pyrolysis temperature, soil pH, and aging period. Environ Sci Pollut Res Int. 2018;25(26):25681–25689