Deltarasin

产品说明书

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Chemical Structure| 1440898-61-2 同义名 : -
CAS号 : 1440898-61-2
货号 : A214777
分子式 : C40H37N5O
纯度 : 96%
分子量 : 603.75
MDL号 : MFCD26793865
存储条件：

Pure form Keep in dark place, sealed in dry, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
靶点

  • PDE

    PDEδ , Kd:38 nM
描述 Deltarasin is a small molecular inhibitor of KRAS-PDEδ interaction with Kd of 38 nM for binding to purified PDEδ.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.66mL

0.33mL

0.17mL

8.28mL

1.66mL

0.83mL

16.56mL

3.31mL

1.66mL
参考文献

[1]Zimmermann G, Papke B, et al. Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signalling. Nature. 2013 May 30;497(7451):638-42.