Miconazole
产品说明书
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同义名 : | R18134 |
| CAS号 : | 22916-47-8 | |
| 货号 : | A209924 | |
| 分子式 : | C18H14Cl4N2O | |
| 纯度 : | 99% | |
| 分子量 : | 416.13 | |
| MDL号 : | MFCD00216019 | |
| 存储条件： |
Pure form Sealed in dry, room temperature In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Miconazole is an imidazole antifungal agent. This agent is distinguished from other azoles by possessing two mechanisms of action. The first mechanism is shared with other azoles and involves the inhibition of ergosterol synthesis. Another mechanism involves inhibition of peroxidases, which results in the accumulation of peroxide within the cell resulting in cell death. Miconazole remains a highly prescribed treatment for vaginal candidiasis[3]. Miconazole was more effective than nystatin for thrush. For HIV-infected patients, there was no significant difference in the efficacy between miconazole and other antifungals. For denture wearers, microwave therapy was significantly better than miconazole. No significant difference was found in the safety evaluation between miconazole and other treatments[4]. In addition, miconazole promoted functional recovery on ischemic stroke model via stimulating post-ischemic neurogenesis[5]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
2.40mL 0.48mL 0.24mL |
12.02mL 2.40mL 1.20mL |
24.03mL 4.81mL 2.40mL |
| 参考文献 |
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