生物活性 | |||
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描述 | MTK458 is an orally active brain-penetrant PINK1 activator. MTK458 interacts with PINK1 and stabilizes an active heterocomplex, thereby augmenting mitophagy. MTK458 is applicable for investigating Parkinson's disease [1]. |
实验方案 | |||
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1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
3.01mL 0.60mL 0.30mL |
15.05mL 3.01mL 1.50mL |
30.09mL 6.02mL 3.01mL |
参考文献 |
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