Firocoxib
产品说明书
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同义名 : | ML 1785713 |
| CAS号 : | 189954-96-9 | |
| 货号 : | A196334 | |
| 分子式 : | C17H20O5S | |
| 纯度 : | 99% | |
| 分子量 : | 336.4 | |
| MDL号 : | MFCD09837800 | |
| 存储条件： |
Pure form Sealed in dry, store in freezer, under -20°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | The COX‐2 isoform is constitutively expressed in a range of tissues and organs, and it is primarily induced by damage or tissue injury as a proinflammatory inducible enzyme and is responsible for the production of inducible enzymes which are converted into various eicosanoids[3]. Firocoxib is a COX-2 selective NSAID. Cats receiving 3 mg/kg firocoxib had lower postoperative pain scores (both Colorado pain scale scores and composite pain scores) than those in the control group[4]. Treatment with firocoxib orally at a dose rate of 5.7 to 8.5 mg/kg prior to induction of acute arthritis in dogs resulted in a high level of analgesia from the first post-treatment assessment at 3.5 h through 24 h post-treatment[5]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
2.97mL 0.59mL 0.30mL |
14.86mL 2.97mL 1.49mL |
29.73mL 5.95mL 2.97mL |
| 参考文献 |
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