Fmoc-Val-Cit-PAB-OH
产品说明书
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同义名 : | Fmoc-Val-Cit-PAB |
| CAS号 : | 159858-22-7 | |
| 货号 : | A192152 | |
| 分子式 : | C33H39N5O6 | |
| 纯度 : | 98% | |
| 分子量 : | 601.69 | |
| MDL号 : | MFCD22417106 | |
| 存储条件： |
Pure form Sealed in dry, store in freezer, under -20°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Fmoc-Val-Cit-PAB is an ADC linker, the Val-Cit group of which will be specifically cleaved by catepsin B. Through the link with Fmoc-Val-Cit-PAB-OH, the ADC payload will be released only in the cell as the enzyme catepsin B is only present in the lysosome of cell. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
1.66mL 0.33mL 0.17mL |
8.31mL 1.66mL 0.83mL |
16.62mL 3.32mL 1.66mL |
