RIG012

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Chemical Structure| 2642218-43-5 同义名 : -
CAS号 : 2642218-43-5
货号 : A1904735
分子式 : C23H21NO3
纯度 : 98%
分子量 : 359.42
MDL号 : N/A
存储条件：

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 RIG012, a potent RIG-I inhibitor, has an IC50 of 0.71 μM in the NADH-coupled ATPase assay, effectively inhibiting IFN-β and ISG hRsad2 expression[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.78mL

0.56mL

0.28mL

13.91mL

2.78mL

1.39mL

27.82mL

5.56mL

2.78mL
参考文献

[1]David C Rawling, et al. Small-Molecule Antagonists of the RIG-I Innate Immune Receptor. ACS Chem Biol. 2020 Feb 21;15(2):311-317.

[2]Qin HX, et al. Synergistic antitumor activity of reversine combined with aspirin in cervical carcinoma in vitro and in vivo. Cytotechnology. 2013 Aug;65(4):643-53.