XEN723
产品说明书
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同义名 : | - |
| CAS号 : | 1072803-08-7 | |
| 货号 : | A189517 | |
| 分子式 : | C21H20FN5O2S | |
| 纯度 : | 99%+ | |
| 分子量 : | 425.48 | |
| MDL号 : | MFCD30533326 | |
| 存储条件： |
Pure form Sealed in dry, store in freezer, under -20°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
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| 描述 | XEN723, a new and powerful thiazolylimidazolidinone class inhibitor of Stearoyl-CoA Desaturase (SCD1), exhibits IC50 values of 45 nM in mouse and 524 nM in HepG2 cells. It shows an enhancement in SCD1 in vitro potency by over 560 times compared to the initial hit in HTS[1]. | ||
| 实验方案 | |||
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| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
2.35mL 0.47mL 0.23mL |
11.75mL 2.35mL 1.18mL |
23.50mL 4.70mL 2.35mL |
| 参考文献 |
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