ML241 HCl

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Chemical Structure| 2070015-13-1 同义名 : ML241 hydrochloride
CAS号 : 2070015-13-1
货号 : A184320
分子式 : C23H25ClN4O
纯度 : 99%
分子量 : 408.92
MDL号 : -
存储条件：

Pure form Inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 ML241 hydrochloride is a potent and selective inhibitors of p97 ATPase with IC50 values of 100 nM.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.45mL

0.49mL

0.24mL

12.23mL

2.45mL

1.22mL

24.45mL

4.89mL

2.45mL
参考文献

[1]Chou TF, Bulfer SL, et al. Specific inhibition of p97/VCP ATPase and kinetic analysis demonstrate interaction between D1 and D2 ATPase domains. J Mol Biol. 2014 Jul 29;426(15):2886-99.

[2]Chou TF, Li K, et al. Structure-activity relationship study reveals ML240 and ML241 as potent and selective inhibitors of p97 ATPase. ChemMedChem. 2013 Feb;8(2):297-312.