RSH-7

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Chemical Structure| 2764609-97-2 同义名 : -
CAS号 : 2764609-97-2
货号 : A1810635
分子式 : C22H25FN8O
纯度 : 99%+
分子量 : 436.49
MDL号 : N/A
存储条件：

Pure form Keep in dark place, sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 RSH-7 exhibits potent inhibition of both BTK and FLT3, with IC50 values of 47 and 12 nM, respectively. Additionally, RSH-7 induces apoptosis and demonstrates antiproliferative effects. RSH-7 effectively suppresses BTK and FLT3 signaling pathways and displays anti-tumor activity [1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.29mL

0.46mL

0.23mL

11.46mL

2.29mL

1.15mL

22.91mL

4.58mL

2.29mL
参考文献

[1]Ran F, et al. Development of novel hydrazidoarylaminopyrimidine-based BTK/FLT3 dual inhibitors with potent in vivo anti-hematological malignancies effects. Eur J Med Chem. 2023 Jan 5;245(Pt 1):114913.