Tubulin inhibitor 11

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Chemical Structure| 2366260-33-3 同义名 : -
CAS号 : 2366260-33-3
货号 : A1810528
分子式 : C22H23N3O3S
纯度 : 99%+
分子量 : 409.5
MDL号 : N/A
存储条件：

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Tubulin inhibitor 11 is a potent and orally active inhibitor of tubulin. It targets the Colchicine binding site on tubulin, inhibits tubulin polymerization, induces mitotic blockade, and promotes apoptosis [1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.44mL

0.49mL

0.24mL

12.21mL

2.44mL

1.22mL

24.42mL

4.88mL

2.44mL
参考文献

[1]Songwen Lin, et al. Optimization of Benzamide Derivatives as Potent and Orally Active Tubulin Inhibitors Targeting the Colchicine Binding Site. J Med Chem. 2022 Dec 22;65(24):16372-16391.