Disufenton sodium

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Chemical Structure| 168021-79-2 同义名 : NXY-059; CPI-22
CAS号 : 168021-79-2
货号 : A175256
分子式 : C11H13NNa2O7S2
纯度 : 99+%
分子量 : 381.33
MDL号 : MFCD09833648
存储条件：

Pure form Sealed in dry, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 NXY-059 is the disulfonyl derivative of the neuroprotective spin trap phenylbutynitrone (PBN), both NXY-059, its parent PBN and their hydrolysis/oxidation product MNT are very powerful scavengers of free radicals.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.62mL

0.52mL

0.26mL

13.11mL

2.62mL

1.31mL

26.22mL

5.24mL

2.62mL
参考文献

[1]Culot M, Mysiorek C, et al. Cerebrovascular protection as a possible mechanism for the protective effects of NXY-059 in preclinical models: an in vitro study. Brain Res. 2009 Oct 19;1294:144-52.

[2]Kuroda S, Tsuchidate R, et al. Neuroprotective effects of a novel nitrone, NXY-059, after transient focal cerebral ischemia in the rat. J Cereb Blood Flow Metab. 1999 Jul;19(7):778-87.