ZLN024

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Chemical Structure| 723249-01-2 同义名 : -
CAS号 : 723249-01-2
货号 : A171505
分子式 : C13H13BrN2OS
纯度 : 99%+
分子量 : 325.22
MDL号 : MFCD05155678
存储条件：

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 ZLN024 is an allosteric activator of AMPK, directly enhancing the activity of various AMPK heterotrimers, specifically AMPK α1β1γ1, α2β1γ1, α1β2γ1, and α2β2γ1, with EC50 values of 0.42 µM, 0.95 µM, 1.1 µM, and 0.13 µM respectively.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.07mL

0.61mL

0.31mL

15.37mL

3.07mL

1.54mL

30.75mL

6.15mL

3.07mL
参考文献

[1]Zhang LN, et al. Novel small-molecule AMP-activated protein kinase allosteric activator with beneficial effects in db/db mice. PLoS One. 2013 Aug 20;8(8):e72092.