NFATc1-IN-1

产品说明书

Print
Chemical Structure| 1912422-56-0 同义名 : -
CAS号 : 1912422-56-0
货号 : A1671418
分子式 : C13H8F2INO2
纯度 : 99%+
分子量 : 375.1
MDL号 : -
存储条件：

Pure form Keep in dark place, sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 NFATc1-IN-1 is a potent inhibitor of RANKL-induced osteoclast formation, demonstrating an IC50 of 1.57 μM. It exhibits anti-osteoclastogenic effects by reducing RANKL-induced NFATc1 nuclear translocation and is suitable for research into osteoclastic diseases[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.67mL

0.53mL

0.27mL

13.33mL

2.67mL

1.33mL

26.66mL

5.33mL

2.67mL
参考文献

[1]Boxer MB, et al. Evaluation of substituted N,N'-diarylsulfonamides as activators of the tumor cell specific M2 isoform of pyruvate kinase. J Med Chem. 2010 Feb 11;53(3):1048-55.