N6-(4-Hydroxybenzyl)adenosine

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Chemical Structure| 110505-75-4 同义名 : Para-topolin riboside
CAS号 : 110505-75-4
货号 : A163624
分子式 : C17H19N5O5
纯度 : 99%
分子量 : 373.36
MDL号 : MFCD18641957
存储条件:

Pure form Keep in dark place, sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 N6-(4-Hydroxybenzyl)adenosine is an inhibitor of platelet aggregation induced in vitro by collagen and their activity range was demonstrated (IC50: 6.77-141 μM).
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.68mL

0.54mL

0.27mL

13.39mL

2.68mL

1.34mL

26.78mL

5.36mL

2.68mL

参考文献

[1]Vistoli G, Brizzolari A, et al. Naturally occurring N(6)-substituted adenosines (cytokinin ribosides) are in vitro inhibitors of platelet aggregation: an in silico evaluation of their interaction with the P2Y(12) receptor. Bioorg Med Chem Lett. 2014 Dec 15;24(24):5652-5655.

[2]Tang C, Wang L, Cheng M, et al. [Determination of N6-(4-hydroxybenzyl) adenine riboside in rat plasma by ultra performance liquid chromatography-quadrupole time of flight mass spectrometry] . Se Pu. 2015 Jul;33(7):699-703. Chinese.