Betahistine EP Impurity C
产品说明书
 |
同义名 : | NSC19005; Betahistine Impurity C |
| CAS号 : | 5452-87-9 | |
| 货号 : | A163510 | |
| 分子式 : | C15H19N3 | |
| 纯度 : | 97% | |
| 分子量 : | 241.33 | |
| MDL号 : | MFCD28157290 | |
| 存储条件： |
Pure form Sealed in dry, room temperature In solvent -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Betahistine EP Impurity C is an impurity of Betahistine[1].Betahistine EP Impurity C is a potent, highly orally active and well tolerated histamine H1 receptor agonist and H3 receptor antagonist used in the study of rheumatoid arthritis (RA)[2][3].Betahistine EP Impurity C inhibited [125I]iodoproxyfan binding on CHO (rH3(445)R) and CHO (hH3(445)R) cell membranes in the range of concentrations less than 10 μM, with IC50 values of 1.9 μM and 3.3 μM, respectively, and Ki values of 1.4 μM and 2.5μM, respectively[3]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
4.14mL 0.83mL 0.41mL |
20.72mL 4.14mL 2.07mL |
41.44mL 8.29mL 4.14mL |
