AZD-9574
产品说明书
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同义名 : | - |
| CAS号 : | 2756333-39-6 | |
| 货号 : | A1601840 | |
| 分子式 : | C21H22F2N6O2 | |
| 纯度 : | 99%+ | |
| 分子量 : | 428.44 | |
| MDL号 : | N/A | |
| 存储条件： |
Pure form Sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
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| 描述 | AZD-9574, a potent brain-penetrant PARP1 inhibitor, demonstrates over 8000-fold selectivity for PARP1 over PARP2/3/5a/6. It selectively inhibits and traps PARP1 at single-strand break sites and is researched for use in HRD+ breast cancer and advanced solid malignancies[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
2.33mL 0.47mL 0.23mL |
11.67mL 2.33mL 1.17mL |
23.34mL 4.67mL 2.33mL |
| 参考文献 |
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