Cjoc42

产品说明书

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Chemical Structure| 2171519-89-2 同义名 : -
CAS号 : 2171519-89-2
货号 : A1600968
分子式 : C20H21N3O5S
纯度 : 98%+
分子量 : 415.46
MDL号 : N/A
存储条件：

Pure form Inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Cjoc42 is a compound with the ability to bind to gankyrin, inhibiting its activity in a dose-dependent manner. Cjoc42 prevents the decrease in p53 protein levels typically induced by high levels of gankyrin and restores p53-dependent transcription and DNA damage sensitivity [1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.41mL

0.48mL

0.24mL

12.03mL

2.41mL

1.20mL

24.07mL

4.81mL

2.41mL
参考文献

[1]Chattopadhyay A, et al. Discovery of a small-molecule binder of the oncoprotein gankyrin that modulates gankyrin activity in the cell. Sci Rep. 2016;6:23732.