EAAT2 activator 1

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Chemical Structure| 892415-28-0 同义名 : -
CAS号 : 892415-28-0
货号 : A1554654
分子式 : C16H11ClFN3S
纯度 : 98%+
分子量 : 331.8
MDL号 : N/A
存储条件：

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 EAAT2 activator 1 is a potent activator of excitatory amino acid transporter 2 (EAAT2), the major glutamate transporter responsible for removing glutamate from synapses. EAAT2 activator 1 dose-dependently increases EAAT2 protein levels [1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.01mL

0.60mL

0.30mL

15.07mL

3.01mL

1.51mL

30.14mL

6.03mL

3.01mL
参考文献

[1]Xing X, et al. Structure-activity relationship study of pyridazine derivatives as glutamate transporter EAAT2 activators. Bioorg Med Chem Lett. 2011;21(19):5774-5777.