GsMTx4 TFA
产品说明书
 |
同义名 : | - |
| CAS号 : | N/A | |
| 货号 : | A1552284 | |
| 分子式 : | C185H273N49O45S6.xC2HF3O2 | |
| 纯度 : | 98% | |
| 分子量 : | 4095.84 (free base) | |
| MDL号 : | N/A | |
| 存储条件： |
Pure form Sealed in dry, under -80°C In solvent -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | GsMTx4 TFA is a spider venom peptide that specifically inhibits cation-permeable mechanosensitive channels (MSCs) in the Piezo and TRP channel families. It also blocks cation-selective stretch-activated channels (SACs), reducing astrocyte toxicity and microglial reactivity induced by lysophosphatidylcholine (LPC). GsMTx4 TFA serves as a valuable pharmacological tool for exploring the role of these excitatory MSCs in both normal physiological processes and pathological conditions [1] [2] [4] | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
0.24mL 0.05mL 0.02mL |
1.19mL 0.24mL 0.12mL |
2.37mL 0.47mL 0.24mL |
