Mito-LND

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Chemical Structure| 2361564-49-8 同义名 : Mito-Lonidamine
CAS号 : 2361564-49-8
货号 : A1550219
分子式 : C43H45BrCl2N3OP
纯度 : 98%
分子量 : 801.62
MDL号 : MFCD34179532
存储条件：

Pure form Inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Mito-LND (Mito-Lonidamine) is an orally administered, mitochondria-focused inhibitor of oxidative phosphorylation (OXPHOS). It disrupts mitochondrial bioenergetics, promotes the production of reactive oxygen species, and triggers autophagic cell death in lung cancer cells[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.25mL

0.25mL

0.12mL

6.24mL

1.25mL

0.62mL

12.47mL

2.49mL

1.25mL
参考文献

[1]Gang Cheng, et al. Targeting lonidamine to mitochondria mitigates lung tumorigenesis and brain metastasis. Nat Commun. 2019 May 17;10(1):2205.