PD-1/PD-L1-IN-10

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Chemical Structure| 2487550-41-2 同义名 : -
CAS号 : 2487550-41-2
货号 : A1550200
分子式 : C33H31N3O7
纯度 : 99%
分子量 : 581.62
MDL号 : N/A
存储条件：

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 PD-1/PD-L1-IN-10 is an orally bioavailable inhibitor of PD-1/PD-L1 (IC50: 2.7 nM) with robust anticancer activity[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.72mL

0.34mL

0.17mL

8.60mL

1.72mL

0.86mL

17.19mL

3.44mL

1.72mL
参考文献

[1]Yiqiang OuYang, et al. Design, Synthesis, and Evaluation of o-(Biphenyl-3-ylmethoxy)nitrophenyl Derivatives as PD-1/PD-L1 Inhibitors with Potent Anticancer Efficacy In Vivo. J Med Chem. 2021 May 26.