同义名 :	(S)-[10]-Gingerol
	CAS号 :	23513-15-7
	货号 :	A151653
	分子式 :	C21H34O4
	纯度 :	99%+
	分子量 :	350.49
	MDL号 :	MFCD01682694
	存储条件：	Pure form Sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月
	溶解度 :	-
	动物实验配方：

生物活性

描述

10-Gingerol, a natural product isolated and purified from the rhizomes of Zingiber officinale Roscoe. with anti-neuroinflammatory capacity, effectively inhibits the growth of the oral pathogens, and inhibits exogenous ghrelin deacylation, induces [Ca2+]i rise by causing Ca2+ release from the endoplasmic reticulum and Ca2+ influx from non-L-type Ca2+ channels in SW480 cancer cells, and induces apoptosis accompanied by phosphorylation of the mitogen-activated protein kinase (MAPKs) family, c-Jun N-terminal kinase (JNK), p38 MAPK (p38), and extracellular signal-regulated kinase (ERK).

实验方案
	1mg	5mg	10mg
1 mM 5 mM 10 mM	2.85mL 0.57mL 0.29mL	14.27mL 2.85mL 1.43mL	28.53mL 5.71mL 2.85mL

参考文献
[1]Ryu MJ, Chung HS. [10] -Gingerol induces mitochondrial apoptosis through activation of MAPK pathway in HCT116 human colon cancer cells. In Vitro Cell Dev Biol Anim. 2015 Jan;51(1):92-101. [2]Ho SC, Chang KS, Lin CC. Anti-neuroinflammatory capacity of fresh ginger is attributed mainly to 10-gingerol. Food Chem. 2013 Dec 1;141(3):3183-91.