Moroxydine HCl
产品说明书
 |
同义名 : | 盐酸吗啉胍 ;ABOB hydrochloride; Moroxydine (hydrochloride); ABOB, Bimolin, Moroxydine free base, SKF 8898-A, SKF 8898A, Virugon, Virumin, Wirumin; ABOB; Moroxydine hydrochloride |
| CAS号 : | 3160-91-6 | |
| 货号 : | A148537 | |
| 分子式 : | C6H14ClN5O | |
| 纯度 : | 98% | |
| 分子量 : | 207.66 | |
| MDL号 : | MFCD00012798 | |
| 存储条件： |
Pure form Sealed in dry,2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | H-Moroxydine hydrochloride (ABOB hydrochloride) is a synthetic antiviral compound chemically belonging to the series of the heterocyclic biguanidines. It has potential applications against a number of RNA and DNA viruses[3]. At the concentration of 40μgmL-1, Mor (Moroxydine Hydrochloride) and Rib (ribavirin) had a significant protective effect on virus-infected cells. Moreover, the gene expressions of vp5, vp6 and NS66 were significantly inhibited by treatment with Mor or Rib, especially gene expression of the vp5. Mor and Rib as antiviral compounds are effective for the control of GCRV replication and the indirectly regulation of cellular immune response[4]. Moreover, exposing GCRV-infected cell to 6.3 μg mL(-1) of Mor for 96 h avoid ca. 50% apoptosis. Mor blocked the GCRV-induced cytopathic effects and eliminated nucleocapsids in CIK cells to keep the normal morphological structure[5]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
4.82mL 0.96mL 0.48mL |
24.08mL 4.82mL 2.41mL |
48.16mL 9.63mL 4.82mL |
| 参考文献 |
|---|