PF-05381941
产品说明书
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同义名 : | - |
| CAS号 : | 1474022-02-0 | |
| 货号 : | A1483443 | |
| 分子式 : | C27H26N6O2 | |
| 纯度 : | 99%+ | |
| 分子量 : | 466.53 | |
| MDL号 : | - | |
| 存储条件： |
Pure form Sealed in dry, store in freezer, under -20°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | PF-05381941 is a potent dual inhibitor of TAK1/p38α with IC50s of 156 and 186 nM, respectively. PF-05381941 inhibits the release of TNF-α from human peripheral mononuclear (PMN) cells stimulated by LPS, with an IC50 of 8 nM[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
2.14mL 0.43mL 0.21mL |
10.72mL 2.14mL 1.07mL |
21.43mL 4.29mL 2.14mL |
