5’-O-DMTr-2’,2’-difluoro-dC(Bz)-3’-CED-phosphoramidite

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Chemical Structure| 142808-44-4 同义名 : -
CAS号 : 142808-44-4
货号 : A1482623
分子式 : C46H50F2N5O8P
纯度 : 97%
分子量 : 869.89
MDL号 : N/A
存储条件：

Pure form Inert atmosphere, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 5’-O-DMTr-2’,2’-difluoro-dC(Bz)-3’-CED-phosphoramidite is classified as a purine nucleoside analog, known for its extensive antitumor capabilities, particularly against slow-growing lymphoid cancers. These compounds exert their anticancer effects primarily through the inhibition of DNA synthesis and the induction of apoptotic processes[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.15mL

0.23mL

0.11mL

5.75mL

1.15mL

0.57mL

11.50mL

2.30mL

1.15mL
参考文献

[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.