ABC1183
产品说明书
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同义名 : | - |
| CAS号 : | 1042735-18-1 | |
| 货号 : | A1465429 | |
| 分子式 : | C18H14N4OS | |
| 纯度 : | 99% | |
| 分子量 : | 334.39 | |
| MDL号 : | MFCD32204423 | |
| 存储条件： |
Pure form Keep in dark place, inert atmosphere, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | ABC1183, an oral inhibitor selective for both GSK3 and CDK9, blocks GSK3β, GSK3α, and CDK9/cyclin T1 with IC50s of 657 nM, 327 nM, and 321 nM, respectively. It exhibits properties that are both anti-inflammatory and anti-tumorigenic[1]. When applied at 3 μM for 24 hours, ABC1183 impedes the progression of the cell cycle, thereby influencing cellular proliferation[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
2.99mL 0.60mL 0.30mL |
14.95mL 2.99mL 1.50mL |
29.91mL 5.98mL 2.99mL |
