YYA-021

产品说明书

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Chemical Structure| 144217-65-2 同义名 : -
CAS号 : 144217-65-2
货号 : A139683
分子式 : C18H27N3O2
纯度 : 99%+
分子量 : 317.43
MDL号 : MFCD00738763
存储条件:

Pure form Keep in dark place, sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 YYA-021, a compact CD4 mimetic, blocks HIV entry and exhibits potent anti-HIV properties coupled with minimal cytotoxicity[1][2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.15mL

0.63mL

0.32mL

15.75mL

3.15mL

1.58mL

31.50mL

6.30mL

3.15mL

参考文献

[1]Otsuki H, Hishiki T, et al. Generation of a replication-competent simian-human immunodeficiency virus, the neutralization sensitivity of which can be enhanced in the presence of a small-molecule CD4 mimic. J Gen Virol. 2013 Dec;94(Pt 12):2710-6.

[2]Hashimoto C, Narumi T, et al. A CD4 mimic as an HIV entry inhibitor: pharmacokinetics. Bioorg Med Chem. 2013 Dec 15;21(24):7884-9.