PKM2 activator 2

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Chemical Structure| 1186660-06-9 同义名 : -
CAS号 : 1186660-06-9
货号 : A1395919
分子式 : C20H18F2N2O4S2
纯度 : 97%
分子量 : 452.49
MDL号 : -
存储条件：

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 PKM2 activator 2 is a potent activator of pyruvate kinase M2 (PKM2) with an AC50 of 66 nM, capable of restoring normal glycolytic metabolism in cells[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.21mL

0.44mL

0.22mL

11.05mL

2.21mL

1.10mL

22.10mL

4.42mL

2.21mL
参考文献

[1]Saha, Suchandrima, et al. The dual-hit metabolic modulator LDCA synergistically potentiates doxorubicin to selectively combat cancer-associated hallmarks. RSC Advances, 7(84), 53322–53333. doi:10.1039/c7ra08625c.