Mycophenolic acid sodium

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Chemical Structure| 37415-62-6 同义名 : -
CAS号 : 37415-62-6
货号 : A1378826
分子式 : C17H19NaO6
纯度 : 98%
分子量 : 342.32
MDL号 : MFCD01723176
存储条件:

Pure form Inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 Mycophenolic acid sodium is an effective uncompetitive inhibitor of inosine monophosphate dehydrogenase (IMPDH) with an EC50 of 0.24 µM. It showcases antiviral capabilities against various RNA viruses, including influenza, and acts as an immunosuppressive agent with antiangiogenic and antitumor properties[1].[2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.92mL

0.58mL

0.29mL

14.61mL

2.92mL

1.46mL

29.21mL

5.84mL

2.92mL

参考文献

[1]Stephen R Welch, et al. Screening and Identification of Lujo Virus Inhibitors Using a Recombinant Reporter Virus Platform. Viruses. 2021 Jun 28;13(7):1255.

[2]Sophie Domhan, et al. Molecular mechanisms of the antiangiogenic and antitumor effects of mycophenolic acid. Mol Cancer Ther. 2008 Jun;7(6):1656-68.