ALC-0315

产品说明书

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Chemical Structure| 2036272-55-4 同义名 : -
CAS号 : 2036272-55-4
货号 : A1375212
分子式 : C48H95NO5
纯度 : 97%
分子量 : 766.27
MDL号 : MFCD33402175
存储条件:

Pure form Sealed in dry, room temperature

In solvent -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 ALC-0315 is an ionizable aminolipid responsible for mRNA compaction, aiding in mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be utilized to form lipid nanoparticle (LNP) delivery vehicles, which have been employed in mRNA COVID-19 vaccine research [1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.30mL

0.26mL

0.13mL

6.53mL

1.30mL

0.65mL

13.05mL

2.61mL

1.30mL

参考文献

[1]Moghimi SM. Allergic Reactions and Anaphylaxis to LNP-Based COVID-19 Vaccines. Mol Ther. 2021;29(3):898-900.