Lenalidomide-4-aminomethyl HCl

产品说明书

Print
Chemical Structure| 444289-05-8 同义名 : Lenalidomide-4-aminomethyl hydrochloride
CAS号 : 444289-05-8
货号 : A1370502
分子式 : C14H16ClN3O3
纯度 : 97%
分子量 : 309.75
MDL号 : MFCD32703223
存储条件:

Pure form Inert atmosphere, room temperature

In solvent -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 Lenalidomide-4-aminomethyl hydrochloride serves as the Lenalidomide-based cereblon (CRBN) ligand employed in CRBN protein recruitment. It can be tethered to a protein ligand via a linker to create a PROTAC[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.23mL

0.65mL

0.32mL

16.14mL

3.23mL

1.61mL

32.28mL

6.46mL

3.23mL

参考文献

[1]Scheepstra M, et al. Bivalent Ligands for Protein Degradation in Drug Discovery. Comput Struct Biotechnol J. 2019;17:160-176. Published 2019 Jan 25.