DCZ0415

产品说明书

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Chemical Structure| 2242470-43-3 同义名 : -
CAS号 : 2242470-43-3
货号 : A1364817
分子式 : C23H20N2O2
纯度 : 98%
分子量 : 356.42
MDL号 : MFCD03349596
存储条件：

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 DCZ0415, an effective TRIP13 inhibitor, disrupts nonhomologous end joining repair and suppresses NF-κB activity. It exhibits anti-myeloma effects in vitro, and in primary cells from drug-resistant myeloma patients[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.81mL

0.56mL

0.28mL

14.03mL

2.81mL

1.40mL

28.06mL

5.61mL

2.81mL
参考文献

[1]Wang Y, et al. A Small Molecule Inhibitor Targeting TRIP13 suppresses multiple myeloma progression. Cancer Res. 2019 Nov 15. pii: canres.3987.2018.