EBOV/MARV-IN-1

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Chemical Structure| 2479465-67-1 同义名 : -
CAS号 : 2479465-67-1
货号 : A1359565
分子式 : C25H30F3N3O2
纯度 : 99%+
分子量 : 461.52
MDL号 : N/A
存储条件：

Pure form Inert atmosphere, room temperature

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 EBOV/MARV-IN-1 is a potent inhibitor of Ebola virus (EBOV) and Marburg virus (MARV), demonstrating broad-spectrum activity (EC50=0.31 and 0.82 µM, respectively) and low cytotoxicity (SI>100) in HeLa cells [1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.17mL

0.43mL

0.22mL

10.83mL

2.17mL

1.08mL

21.67mL

4.33mL

2.17mL
参考文献

[1]Gaisina IN, et, al. Discovery and Structural Optimization of 4-(Aminomethyl)benzamides as Potent Entry Inhibitors of Ebola and Marburg Virus Infections. J Med Chem. 2020 Jul 9;63(13):7211-7225.