Mcl-1/Bcl-2 PROTAC compound C3

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Chemical Structure| 2163793-38-0 同义名 : PROTAC Mcl1 degrader-1
CAS号 : 2163793-38-0
货号 : A1339690
分子式 : C45H45BrN6O8S
纯度 : 98%
分子量 : 909.84
MDL号 : MFCD32201080
存储条件：

Pure form Inert atmosphere, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.10mL

0.22mL

0.11mL

5.50mL

1.10mL

0.55mL

10.99mL

2.20mL

1.10mL
参考文献

[1]Wang Z, He N, Guo Z, Niu C, Song T, Guo Y, Cao K, Wang A, Zhu J, Zhang X, Zhang Z. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163. doi: 10.1021/acs.jmedchem.9b00919. Epub 2019 Aug 21. PMID: 31389699.