AZD-8529 mesylate

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Chemical Structure| 1314217-69-0 同义名 : -
CAS号 : 1314217-69-0
货号 : A1329231
分子式 : C25H28F3N5O6S
纯度 : 99%+
分子量 : 583.58
MDL号 : MFCD32645412
存储条件:

Pure form Keep in dark place, inert atmosphere, room temperature

In solvent -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 AZD-8529 mesylate is a potent, highly selective and orally active mGluR2-positive modulator with an EC50 of 285 nM and no positive modulation of mGluR1, 3, 4, 5, 6, 7 and 8 isoforms at high concentration[1].AZD-8529 mesylate enhances the effect of glutamate on mGluR2 with an EC50 of 195 nM[1].At a concentration of 25 μM, AZD-8529 mesylate does not induce an antagonistic response to mGluR[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.71mL

0.34mL

0.17mL

8.57mL

1.71mL

0.86mL

17.14mL

3.43mL

1.71mL