同义名 :	Fmoc-leucine; N-FMOC-leucine; FMOC-Leu; FMOC-L-Leucine; NSC 334290; NPC 15199
	CAS号 :	35661-60-0
	货号 :	A132224
	分子式 :	C21H23NO4
	纯度 :	98%
	分子量 :	353.41
	MDL号 :	MFCD00037133
	存储条件：	Pure form Sealed in dry,2-8°C In solvent -20°C:3-6个月-80°C:12个月
	溶解度 :	-
	动物实验配方：

生物活性
描述	Fmoc-leucine serves as a selective modulator of PPARγ, triggering its activation with less potency yet comparable maximal effectiveness to that of rosiglitazone. It enhances insulin sensitivity across various mouse models, including normal, diet-induced glucose-intolerant, and diabetic db/db mice. Additionally, Fmoc-leucine is characterized by reduced adipogenic activity[1].

实验方案
	1mg	5mg	10mg
1 mM 5 mM 10 mM	2.83mL 0.57mL 0.28mL	14.15mL 2.83mL 1.41mL	28.30mL 5.66mL 2.83mL

参考文献

[1]References are publications that support the biological activity of the product. Burch et al (1991) N-(Fluorenyl-9-methoxycarbonyl) amino acids, a class of anti-inflammatory agents with a different mechanism of action. Proc.Natl.Acad.Sci.U.S.A. 88 355 PMID: 1824872 Jan et al (2000) NPC-15199, a novel anti-inflammatory agent, mobilizes intracellular Ca2+ in bladder female transitional carcinoma (BFTC) cells. Chin.J.Physiol. 43 29 PMID: 10857466 Miller et al (1993) Guinea pig ileitis is attenuated by the leumidin N-(fluorenyl-9-methoxycarbonyl)leucine (NPC 15199). J.Pharmacol.Exp.Ther. 266 468 PMID: 8392562 If you know of a relevant reference for NPC 15199, please let us know.