FPR-A14
产品说明书
 |
同义名 : | - |
| CAS号 : | 329691-12-5 | |
| 货号 : | A1282528 | |
| 分子式 : | C23H20N2O5 | |
| 纯度 : | 99%+ | |
| 分子量 : | 404.42 | |
| MDL号 : | MFCD01065721 | |
| 存储条件： |
Pure form Sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | FPR-A14 is a potent FPR agonist. FPR-A14 induces cell differentiation[1][2]. FPR-A14 activates Ca2+ release from human neutrophils with an EC50 value of 630 nM. FPR-A14 is a neutrophil chemotaxis inducer that dose-dependently induces neutrophil migration with an EC50 value of 42 nM[1] . In mouse neuroblastoma N2a cells, FPR-A14 significantly increased the cell differentiation rate in the concentration range of 1-10 μM for 48 h. The concentrations with responses were 4 μM (32. 0%), 6 μM (64. 9%), 8 μM (89. 1%) and 10 μM (93. 3%), respectively. At a concentration of 100 μM, FPRa14 produced similar effects in IMR-32 and SH-SY5Y cells[2]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
2.47mL 0.49mL 0.25mL |
12.36mL 2.47mL 1.24mL |
24.73mL 4.95mL 2.47mL |
