SphK1&2-IN-1

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Chemical Structure| 1415662-57-5 同义名 : -
CAS号 : 1415662-57-5
货号 : A1281647
分子式 : C14H14N2O3S
纯度 : 99%+
分子量 : 290.34
MDL号 : -
存储条件:

Pure form Sealed in dry, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月

溶解度 : -
生物活性
描述 SphK1&2-IN-1, a SphK inhibitor targeting SphK1 and SphK2, possesses thermal stability [1][2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.44mL

0.69mL

0.34mL

17.22mL

3.44mL

1.72mL

34.44mL

6.89mL

3.44mL

参考文献

[1]Kuwano K, et al. 2-[4-[(5,6-diphenylpyrazin-2-yl)(isopropyl)amino]butoxy]-N-(methylsulfonyl)acetamide (NS-304), an orally available and long-acting prostacyclin receptor agonist prodrug. J Pharmacol Exp Ther. 2007 Sep;322(3):1181-8.

[2]Nong W, et al. Synthesis and biological evaluation of a new series of cinnamic acid amide derivatives as potent haemostatic agents containing a 2-aminothiazole substructure. Bioorg Med Chem Lett. 2017 Sep 15;27(18):4506-4511.