PTUPB

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Chemical Structure| 1287761-01-6 同义名 : -
CAS号 : 1287761-01-6
货号 : A1258087
分子式 : C26H24F3N5O3S
纯度 : 99%+
分子量 : 543.56
MDL号 : MFCD32701914
存储条件：

Pure form Sealed in dry,2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 PTUPB effectively inhibits both sEH and COX-2 enzymes, demonstrating IC50 values of 0.9 nM and 1.26 μM, respectively[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.84mL

0.37mL

0.18mL

9.20mL

1.84mL

0.92mL

18.40mL

3.68mL

1.84mL
参考文献

[1]Sun CC, et al. PTUPB ameliorates high-fat diet-induced non-alcoholic fatty liver disease via inhibiting NLRP3 inflammasome activation in mice. Biochem Biophys Res Commun. 2020 Mar 19;523(4):1020-1026.

[2]Zhang G, et al. Dual inhibition of cyclooxygenase-2 and soluble epoxide hydrolase synergistically suppresses primary tumor growth and metastasis. Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):11127-32.