BAY 2416964

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Chemical Structure| 2242464-44-2 同义名 : -
CAS号 : 2242464-44-2
货号 : A1257495
分子式 : C18H18ClN5O3
纯度 : 99%+
分子量 : 387.82
MDL号 : MFCD32693912
存储条件：

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 BAY 2416964 is a potent, orally active antagonist of the aryl hydrocarbon receptor (AHR), derived from patent WO2018146010A1, example 192, with an IC50 of 341 nM. It holds potential for the treatment of solid tumors[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.58mL

0.52mL

0.26mL

12.89mL

2.58mL

1.29mL

25.79mL

5.16mL

2.58mL
参考文献

[1]Ilona GUTCHER, et al. 2-heteroaryl-3-oxo-2,3-dihydropyridazine-4-carboxamides for the treatment of cancer. WO2018146010A1