VUF11207 fumarate
产品说明书
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同义名 : | - |
| CAS号 : | 1785665-61-3 | |
| 货号 : | A1251826 | |
| 分子式 : | C31H39FN2O8 | |
| 纯度 : | 98% | |
| 分子量 : | 586.65 | |
| MDL号 : | MFCD27991278 | |
| 存储条件： |
Pure form Keep in dark place, inert atmosphere, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | VUF11207 fumarate is a CXCR7 agonist that binds specifically to CXCR7. At a concentration of 0.17 nM for 5 days, VUF11207 fumarate inhibits RANKL- and TNF-α-induced osteoclastogenesis by inhibiting CXCL12 in osteoclast precursor cells and inhibits the phosphorylation of ERK[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
1.70mL 0.34mL 0.17mL |
8.52mL 1.70mL 0.85mL |
17.05mL 3.41mL 1.70mL |
