CID44216842

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Chemical Structure| 1222513-26-9 同义名 : Cdc42-IN-1
CAS号 : 1222513-26-9
货号 : A1249675
分子式 : C22H20BrN3O3S
纯度 : 99%+
分子量 : 486.38
MDL号 : MFCD28009507
存储条件：

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 CID44216842 (Cdc42-IN-1) is a highly effective inhibitor that selectively targets Cdc42 by binding to its guanine nucleotide-binding site. In GTP binding assays, the EC50 values for Cdc42 WT and the Cdc42Q61L mutant are 1.0 μM and 1.2 μM, respectively. Similarly, in GDP binding assays, the EC50 values for Cdc42 WT and the Cdc42Q61L mutant are 0.3 μM and 0.5 μM, respectively. This compound serves as a valuable molecular probe [1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.06mL

0.41mL

0.21mL

10.28mL

2.06mL

1.03mL

20.56mL

4.11mL

2.06mL
参考文献

[1]Lin Hong, et al. Characterization of a Cdc42 Protein Inhibitor and Its Use as a Molecular Probe. J Biol Chem. 2013 Mar 22;288(12):8531-43.