DIF-3

产品说明书

Print
Chemical Structure| 113411-17-9 同义名 : -
CAS号 : 113411-17-9
货号 : A1249412
分子式 : C13H17ClO4
纯度 : 99%
分子量 : 272.72
MDL号 : MFCD05865230
存储条件：

Pure form Keep in dark place, sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 DIF-3 reduces the expression levels of cyclin D1 and c-Myc by promoting their degradation via the activation of GSK-3β. It inhibits proteins related to the Wnt/β-catenin signaling pathway in DLD-1 cells and exerts a potent antiproliferative effect on the human cervical cancer cell line HeLa, inducing cyclin D1 degradation and inhibiting cyclin D1 mRNA expression[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.67mL

0.73mL

0.37mL

18.33mL

3.67mL

1.83mL

36.67mL

7.33mL

3.67mL
参考文献

[1]Naoya Kubokura , et al. Differentiation-inducing factor-3 inhibits intestinal tumor growth in vitro and in vivo. J Pharmacol Sci. 2015 Apr;127(4):446-55.