Vebicorvir
产品说明书
 |
同义名 : | ABI-H0731 |
| CAS号 : | 2090064-66-5 | |
| 货号 : | A1227262 | |
| 分子式 : | C19H12F3N3O4S2 | |
| 纯度 : | 98%+ | |
| 分子量 : | 467.44 | |
| MDL号 : | MFCD32856555 | |
| 存储条件： |
Pure form Sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Vebicorvir, also known as ABI-H0731, is a first-generation hepatitis B virus (HBV) core protein inhibitor.Vebicorvir inhibits covalent closed-circle DNA (cccDNA) formation in two models of de novo infection, with EC50s ranging from 1.84 μM to 7.3 μM.Vebicorvir inhibits pgRNA, HBeAg and HBsAg production with EC50 values of 2.68 μM, 4.95 μM, and 7.30 μM, respectively.Vebicorvir is an inhibitor of pgRNA encapsulation and rcDNA synthesis[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
2.14mL 0.43mL 0.21mL |
10.70mL 2.14mL 1.07mL |
21.39mL 4.28mL 2.14mL |
