Sirtuin modulator 5

产品说明书

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Chemical Structure| 694469-31-3 同义名 : -
CAS号 : 694469-31-3
货号 : A1227212
分子式 : C24H23N3O4
纯度 : 99%+
分子量 : 417.46
MDL号 : -
存储条件:

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 Sirtuin modulator 5 is a compound that modulates sirtuins. It activates SIRT1 with a DC50 value of <50 μM. Sirtuin modulator 5 can extend cell lifespan and is applicable for research on various diseases, including those associated with aging, stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and flushing, as well as conditions benefiting from enhanced mitochondrial activity [1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.40mL

0.48mL

0.24mL

11.98mL

2.40mL

1.20mL

23.95mL

4.79mL

2.40mL

参考文献

[1]Bestgen B, et al. 2-Aminothiazole Derivatives as Selective Allosteric Modulators of the Protein Kinase CK2. 1. Identification of an Allosteric Binding Site. J Med Chem. 2019 Feb 28;62(4):1803-1816.