SPHINX

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Chemical Structure| 848057-98-7 同义名 : -
CAS号 : 848057-98-7
货号 : A1218646
分子式 : C17H17F3N2O3
纯度 : 99%+
分子量 : 354.32
MDL号 : MFCD07315693
存储条件：

Pure form Sealed in dry, room temperature

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 SPHINX is a specific inhibitor of SRPK1, demonstrating an IC50 value of 0.58 μM. It significantly diminishes Choroidal Neovascularization (CNV) in vivo. SPHINX holds promise for investigating age-related macular degeneration (AMD) [1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.82mL

0.56mL

0.28mL

14.11mL

2.82mL

1.41mL

28.22mL

5.64mL

2.82mL
参考文献

[1]Gammons MV, et al. Topical antiangiogenic SRPK1 inhibitors reduce choroidal neovascularization in rodent models of exudative AMD. Invest Ophthalmol Vis Sci. 2013 Sep 5;54(9):6052-62.