ML192
产品说明书
 |
同义名 : | CID-1434953 |
| CAS号 : | 460331-61-7 | |
| 货号 : | A1210826 | |
| 分子式 : | C20H22N4O2S | |
| 纯度 : | 97% | |
| 分子量 : | 382.48 | |
| MDL号 : | MFCD03127624 | |
| 存储条件： |
Pure form Sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | ML192 is a selective ligand antagonist of GPR55. ML192 inhibited L-α lysophosphatidylinositol or ML186-induced β-arrestin trafficking with IC50 values of 0.70 µM and 0.29 µM, respectively. ML192 significantly inhibited ERK1 in U2OS cells expressing GPRSS. ML192 significantly inhibited the phosphorylation of ERK1/2 in U2OS cells expressing GPRSS, with an IC50 value of 1.1 µM. ML192 reduced PKCβII translocation in wild-type GPR55 receptor cells at concentrations of 10, 30, and 100 µM[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
2.61mL 0.52mL 0.26mL |
13.07mL 2.61mL 1.31mL |
26.15mL 5.23mL 2.61mL |
