Eact
产品说明书
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同义名 : | - |
| CAS号 : | 461000-66-8 | |
| 货号 : | A1209836 | |
| 分子式 : | C22H24N2O5S | |
| 纯度 : | 99%+ | |
| 分子量 : | 428.5 | |
| MDL号 : | MFCD03115431 | |
| 存储条件： |
Pure form Sealed in dry,2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Eact is a selective, potent TMEM16A activator that directly activates TRPV1 channels in sensory nociceptors. Eact activates membrane currents in a concentration-dependent manner in mTRPV1-expressing HEK293T cells with an EC50 of 11.6 ± 2.5 μM. Eact produces itchy, acute nociceptive, and thermal hypersensitivity responses[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
2.33mL 0.47mL 0.23mL |
11.67mL 2.33mL 1.17mL |
23.34mL 4.67mL 2.33mL |
