PD 198306
产品说明书
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同义名 : | - |
| CAS号 : | 212631-61-3 | |
| 货号 : | A1209818 | |
| 分子式 : | C18H16F3IN2O2 | |
| 纯度 : | 97% | |
| 分子量 : | 476.23 | |
| MDL号 : | MFCD08690428 | |
| 存储条件： |
Pure form Sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | PD 198306 is a selective MAPK/ERK kinase inhibitor, which significantly reduces the Streptozocin-induced increase in active ERK1 and 2 levels[1].At a concentration of 10 μM for 36 hours, PD 198306 significantly inhibited Tha-GFP replication by 25%[2].In iPSC cells, at a concentration of 5 μM, PD 198306 significantly reduced Tha-Crimson replication by 20% within 18 hours, but this result could not be confirmed at 36 hours[2]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
2.10mL 0.42mL 0.21mL |
10.50mL 2.10mL 1.05mL |
21.00mL 4.20mL 2.10mL |
